منابع مشابه
Ascorbic acid and 6-deoxy-6-chloro-ascorbic acid: potential anticancer drugs.
The role of ascorbic acid (AA) in prevention and suppression of carcinogenesis has been known for a long time. It was also found that AA may inhibit the growth of some tumor cells in vitro and in vivo. We examined the influence of ascorbic acid and 6-chloro-6-deoxy ascorbic acid (6-Cl-AA) on the growth of various human cell lines: lung fibroblasts (Hef), ovarian adenocarcinoma (OVCAR), colon ad...
متن کامل6-Bromo-1H-indole-3-carboxylic acid
In the title mol-ecule, C(9)H(6)BrNO(2), the dihedral angle between the -COOH group and the ring system is 6 (4)°. In the crystal, pairs of O-H⋯O hydrogen bonds link the mol-ecules into inversion dimers and these dimers are connected via N-H⋯O hydrogen bonds to form layers parallel to the (-101) plane.
متن کاملVitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy.
PURPOSE Metabolomics, or metabolic profiling, is an emerging discipline geared to providing information on a large number of metabolites, as a complement to genomics and proteomics. In the current study, a fluorine-labeled derivative of ascorbic acid (F-ASA), a major antioxidant- and UV-trapping molecule in the aqueous humor and the lens, was used to investigate the extent to which the lens acc...
متن کاملPotential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid
Intravenous administration of high-dose ascorbic acid (AA) has been reported as a treatment for cancer patients. However, cancer patients with renal failure cannot receive this therapy because high-dose AA infusion can have side effects. To solve this problem, we evaluated the antitumor activity of a lipophilic stable AA derivative, 2-O-α-d-glucopyranosyl-6-O-(2-pentylheptanoyl)-l-ascorbic acid...
متن کاملMethyl 5-bromo-6-methylpicolinate
The title compound, C(8)H(8)BrNO(2), does not show any significant inter-molecular π-π or C-H⋯π inter-actions in the crystal packing except for one weak Br⋯Br [3.715 (1) Å] inter-action.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2005
ISSN: 0021-9258
DOI: 10.1074/jbc.m412925200